Table II. XBP1 DC vaccine decreases tumor spontaneous bone marrow metastases
DC VaccinesMice with Bone Marrow Metastases/Mice Used in Experiments
Untreated6/6
XBP15/6
NeuEDhsp704/6
XBP1/NeuEDhsp700/6
  • Tumor-bearing BALB/c mice were untreated or vaccinated by DC (Fig. 2B). On day 30, tumor cells in bone marrow were selected, and data from two independent experiments are shown and were statistically analyzed (26). XBP1/NeuEDhsp70 versus untreated, NeuEDhsp70, or XBP1: p < 0.05.