Table 1.

Proliferative responses of Tr1 cells to CBA, epithelial, food, and control Agsa

Stimuluscpm ± SD
CBA-APC7365 ± 562
Epithelial Ag-APC726 ± 102
Food Ag-APC864 ± 133
OVA-APC768 ± 99
APC only544 ± 87

  • a Splenic APCs from C3H/HeJ mice were incubated with 200 mg/ml CBA, epithelial Ag, food Ag, or OVA overnight. Tr1 cells (2 × 105) were cultured with 2 × 105 APC. [3H]TdR was added to the wells for the last 18 h of a 3-day culture. Results are expressed as mean cpm ± SD of triplicate culture.