Table II.

Chimerism and survival of allografts in wild-type and gene-deficient hosts given ATS, TLI, and donor bone marrow cellsa

Host TypePercentage of Donor-Type Cells Amongst White Blood Cells of HostbFraction of Hosts with Allograft Surviving >100 Days
BALB/c
Wild type51, 54, 56, 57, 58, 58, 58, 60, 60, 61, 64, 6511 /13
CD1−/−<1, <1, 1, 23, 57, 580 /8
IL-4−/−<1, 53, 57, 60, 65, 67, 703 /9
IFN-γ−/−48, 50, 50, 52, 57, 60, 61, 63, 64, 6910 /10
C57BL/6
Wild type57, 62, 63, 70, 70, 72, 74, 77, 77, 78, 78, 7812 /12
Jα281−/−70, 71, 72, 75, 75, 77, 783 /7
IL-4−/−66, 66, 70, 71, 74, 762 /6
IL-10−/−68, 69, 70, 70, 72, 73, 73, 75, 80, 800 /10
  • a Day 28 after bone marrow cell injection (= day 43 after heart transplantation). Adequate blood samples were not available for analysis in some hosts.