Table III.

DC subsets and viral load in HIV-infected individualsa

DC Subsets/IFN-αHIV (<50 copies/ml)HIV (50–5000 copies/ml)HIV (>5000 copies/ml)HIV
MDC0.31 (0.28–0.46), n = 250.26 (0.14–0.67), n = 150.13 (0.10–0.22), n = 24b0.27 (0.17–0.47), n = 53
PDC (CD123+)0.11 (0.08–0.18), n = 260.09 (0.03–0.17), n = 150.09 (0.04–0.19), n = 24, NS0.29 (0.13–0.42), n = 53
PDC (BDCA-2+)0.08 (0.02–0.18), n = 120.11 (0.07–0.17), n = 90.09 (0.06–0.13), n = 12, NS0.37 (0.15–0.50), n = 21
Influenza-IFN-α107 (49–325), n = 1880 (26–180), n = 1493 (36–189), n = 16, NS1468 (626–2094), n = 34
HSV-1-IFN-α164 (57–233), n = 1854 (10–179), n = 1484 (33–173), n = 16, NS912 (672–1790), n = 35
CD4 counts584 (279–694)378 (312–607)425 (271–600)
  • a Results shown are measured in percentage of positive cells and picograms per milliliter for IFN-α, and values are expressed as median (25th–75th percentile).

  • b Statistical significance within the MDC subset is as follows: <50 copies/ml vs >5000 copies/ml, p < 0.0032, and 50–5000 copies/ml vs >5000 copies/ml, p = 0.029, respectively.