DC Subsets/IFN-α | HIV (<50 copies/ml) | HIV (50–5000 copies/ml) | HIV (>5000 copies/ml) | HIV^{−} |
---|---|---|---|---|
MDC | 0.31 (0.28–0.46), n = 25 | 0.26 (0.14–0.67), n = 15 | 0.13 (0.10–0.22), n = 24^{b} | 0.27 (0.17–0.47), n = 53 |
PDC (CD123^{+}) | 0.11 (0.08–0.18), n = 26 | 0.09 (0.03–0.17), n = 15 | 0.09 (0.04–0.19), n = 24, NS | 0.29 (0.13–0.42), n = 53 |
PDC (BDCA-2^{+}) | 0.08 (0.02–0.18), n = 12 | 0.11 (0.07–0.17), n = 9 | 0.09 (0.06–0.13), n = 12, NS | 0.37 (0.15–0.50), n = 21 |
Influenza-IFN-α | 107 (49–325), n = 18 | 80 (26–180), n = 14 | 93 (36–189), n = 16, NS | 1468 (626–2094), n = 34 |
HSV-1-IFN-α | 164 (57–233), n = 18 | 54 (10–179), n = 14 | 84 (33–173), n = 16, NS | 912 (672–1790), n = 35 |
CD4 counts | 584 (279–694) | 378 (312–607) | 425 (271–600) |
a Results shown are measured in percentage of positive cells and picograms per milliliter for IFN-α, and values are expressed as median (25th–75th percentile).
b Statistical significance within the MDC subset is as follows: <50 copies/ml vs >5000 copies/ml, p < 0.0032, and 50–5000 copies/ml vs >5000 copies/ml, p = 0.029, respectively.