Table II.

Differential functional responses of MDC and PDC in HIV-infected individuals

Patients	MDC^a	PDC^a	Influenza IFN-α^b	HSV-1 IFN-α^b	MLR SI^c	CD4 T Cells/mm³	Viral Load (copies/ml)
P183	0.31	0.12	117	98	8	220	50
P187	0.3	0.11	278	158	11.6	388	50
P269	0.55	0.25	388	497	11.4	89	50
P271	0.3	0.11	202	139	11.8	622	50
P272	ND	0.19	309	201	9.6	188	50
P273	0.31	0.1	116	189	11.8	459	50
P275	0.29	0.17	375	218	10.4	598	50
P277	0.21	0.2	98	87	7.6	175	73
P270	0.14	0.12	189	209	9	283	112
P278	0.44	0.18	178	221	12.6	340	132
P185	0.26	0.09	90	ND	9.6	289	2,480
P276	0.41	0.19	312	234	10	1,050	7,150
P184	0.09	0.2	89	220	2.5	313	28,300
P186	0.22	0.19	289	401	7	600	48,600
All patients (n = 14)	0.29 ± 0.03	0.16 ± 0.013	217 ± 29	221 ± 31	9.5 ± 0.7	401 ± 67	6,228 ± 3,835
All controls (n = 8)	0.30 ± 0.035	0.32 ± 0.03	1,459 ± 370	1,113 ± 306	9.22 ± 0.6
p values^d	NS	p = 0.002	p < 0.0003	p < 0.0008	NS

a Results represent percentage of positive cells ± SE. PDC are defined by HLA-DR⁺CD123⁺Lin⁻.
b Viral stimulated IFN-α measured in picograms per milliliter ± SE.
c SI ± SE (SI as defined in Materials and Methods).
d Statistical significance between HIV⁻ and HIV⁺ was performed using the Wilcoxon tests.