Table I.

Patients with newly diagnosed type 1 diabetes and Abs against IA-2 JM

PatientReactivity Against IA-2 Deletion Mutants and IA-2/IA-2β Chimeras
IA-2382–779 mutantJM601–620 chimeraJM601–642 chimeraJM601–682 chimeraJM601–777 chimeraIA-21–620 mutantJM621–642 chimeraJM601–682 inhibited with JM601–620
1+++++++++++
2+++++++++++
3+++++++++++
4+++++++NTa
5+++++++NT
6+++++++NT
7++++++NT
8+++++++++++
9++++++++++++++++++NT
10+++++++++NT
11+++++++++NT
12+++++++++NT
13+++++NT
14+++++NT
15+++++NTNT
16+++NTNT
17++++NTNT
18+NTNT
19+NTNT
  • a NT, Not tested.