Table II.

Methylation at CpA and CpT sites in the IFN-γ promoter is significantly different between cord blood and adult T cellsa

SequencesMethylatedUnmethylated
CD3+/CD45RO
Adult5210458
Cord5369408∗∗∗
CD4+/CD45RO
Adult4510395
Cord120511029∗
CD8+/CD45RO
Adult331296
Cord372331
CD56+/CD16+/CD3
Adult313276
Cord313276
  • a CpA methylation (position −292, −254, −252, −240, −209, and −2) and CpT methylation (position −169, −41 and +42) was scored at specific sites in IFN-γ promoter DNA sequence. The number of methylated and unmethylated sites was scored and a Fisher’s exact test was used to assign p values (∗, = 0.056; ∗∗∗, p < 0.0001).