Table I.

Absolute numbers of tetramer+CD8+ T cells detected in lymphoid organs of immunized or naive HHD micea

Experimental GroupTetramer+CD8+ T Cell Number (×10−3)
SpleenLymph node
ELA26–35+ CpG
1 12.7 <0.2
2 4.2 <0.1
3 18.9 17.1
4 12.9 5.1
ELA26–35 + IFA
10.6<0.1
2 2.2 0.3
3 3.9 0.7
4 1.0 0.1
5 7.2 0.1
ELA26–35+ CpG+ IFA
1 14.3 11.8
2 28.6 10.9
3 18.0 6.3
4 9.3 5.6
5 80.3 12.7
Naive
10.41.3
20.70.7
30.30.3
40.10.1
  • a The absolute numbers of tetramer+CD8+ T lymphocytes were calculated in lymphoid organs of mice analyzed in Fig. 3. The numbers of tetramer+CD8+ T lymphocytes corresponding to a significant difference as compared to naive mice (higher than mean value + SD) are typed in bold.