Table II.

Complementation of V(D)J recombination in SCIDA patient (13-A2 and 07-A1) fibroblasts transfected with a wild-type SCIDA construct (pCMV-SCIDA)

Cell LinepCMV-SCIDACoding (pGG51)Signal (pGG49)
ampr and camrTotal (ampr)R%aampr and camrTotal (ampr)R%b
Control 137637,8809.9109801.02
Control 2301,3602.2151,3201.13
13-A2281,9200.0253285,0800.62
+34749,8406.961127,5201.49
07-A1059,280<0.016225,0000.25
+1,040153,2806.78714,4801.58
  • a R (coding joints) = (ampr and camr)/(Total) × 1,000.

  • b R (signal joints) = (ampr and camr)/(Total) × 100.