Table II.

Vβ-specific CD69 up-regulation on CD8 T cells in response to incubation with CVB4 Ags

SubjectHLA-DR GenotypeVβ Chain
1235678111213141617202122
C103,15XbXXXXXXXXX
C204,15XXXXXXXXXX
C303,15XXXXXXX
C404,15NDND
C503,07XXXX
C601,13XXXXX
C704,04XXXXXXXXXXXX
C803,03XXXX
% positive37.562.55012.5252537.542.85037.537.542.85062.537.550
D103,04XXXX
D201,01XXXXX
D301,08XXXNDNDX
D403,04XXXXXXX
D503,03XXXX
D603,04XXXXXX
D704,07XXXXXXX
D803,13XXXXXXXX
% positive7512.537.525752537.528.637.5062.528.65012.52537.5
Total positive (%)56.331.337.518.85018.837.521.437.512.543.828.650252537.5
  • a C1–8, Control subjects; D1–8, patients with type 1 DM.

  • b X, Positive response to CVB4; ND, not done.