Table I.

Vβ-specific CD69 up-regulation on CD4 T cells in response to incubation with CVB4 Agsa

SubjectHLA-DR GenotypeVβ Chain
1235678111213141617202122
C103,15XbXXXXXXXXX
C204,15XXXXXXXX
C303,15XXX
C404,15XXXNDXNDXX
C503,07XXXXXXXXX
C601,13XXXXXXX
C704,04XXXXXXX
C803,03XXXNDXXX
% positive37.537.5255037.5505071.457.162.52542.9505037.537.5
D103,04XXXXXXXXX
D201,01XXXXXXX
D301,08XXXNDXNDXXX
D403,04XXXXXXXXX
D503,03XXXXXXXX
D603,04XXXXXXNDXX
D704,07XXXXXXXXXXXX
D803,13XXXXXXXXXX
% positive37.57562.5505075100*66.762.5252557.1505062.550
Total positive (%)37.556.343.85043.862.57569.26043.8255050505043.8
  • a C1–8, Control subjects; D1–8, patients with type 1 DM.

  • b X, positive response to CVB4; ND, not done.

  • c , p < 0.05 compared with healthy controls.