Table IV.

Kidney disease in αβ+ T cell-deficient male BXSB recipients of CD3+ T cells from WT BXSB male or female micea

GNBlood Urea NitrogenImmune Complex Deposit Score
Male BXSB→male BXSB TCRα−/−2.9 ± 0.23.0 ± 0.33.0 ± 0.2
Female BXSB→male BXSB TCRα−/−3.0 ± 0.22.8 ± 0.22.8 ± 0.2
WT male BXSB3.4 ± 0.23.0 ± 0.23.1 ± 0.3
  • a GN, blood urea nitrogen, and immune complex deposits of 4-mo-old WT male BXSB and of 9-mo-old αβ+ T cell-deficient male BXSB recipients of WT male or female CD3+ LN T cells (mean ± SEM of five to eight mice per group).