Table I.

Summary of chemokines analyzed for antimicrobial activity by RDA

FamilyChemokineProposed NomenclaturepIAntimicrobial Activitya
CXC (ELR)MIGCXCL911.1+
IP-10CXCL1010.77+
I-TACCXCL1110.67+
CXC (ELR+)IL-8CXCL89.59
ENA-78CXCL58.73
CCMCP-1CCL210.6
MIP-1αCCL34.6
MIP-1βCCL44.48
RANTESCCL59.5
CX3CFractalkine (chemokine domain)CX3CL19.97
CLymphotactinXCL111.35
  • a A negative value (−) indicates that chemokines were not antimicrobial even at 50 μg/ml as measured by RDA.