Table II.

Diabetes incidence in Ins-IL-10 mice backcrossed to NOD mice

Backcross GenerationNOD.Ins-IL-10 Mice
NOD.Ins-IL-10 (H-2g7/g7)NOD.Ins-IL-10 (H-2g7/d)
No. diabetic/total (%)
Fifth (N6)11 /12 (91)0 /10 (0)
Sixth (N7)5 /6 (83)0 /10 (0)
Seventh (N8)6 /6 (100)0 /6 (0)
Eighth (N9)13 /13 (100)0 /7 (0)
Ninth (N10)6 /6 (100)0 /9 (0)
Tenth (N11)11 /11 (100)0 /11 (0)
Total52 /54 (96)0 /53 (0)