Table II.

Phenotype of PBMC stimulated by CpG ODN to secrete cytokinesa

Cell Surface Marker% Positive Cells
A. Phenotype of PBMC activated by D ODN to produce IFN-γ
CD1691
CD5699
CD35
CD14<1
B. Phenotype of PBMC activated by K ODN to produce IL-6
CD8393
CD1470
CD11c69
CD1913
CD16<1
  • a Freshly isolated PBMC were stimulated with K (8 h) or D (24 h) ODN. Cells were fixed, permeabilized, and stained with PE-anti-IL-6 or anti-IFN-γ. Results are representative of 4–10 experiments.