Table I.

ED50/ED30 values for systemic effects of 7-day oral steroid treatment

StudyED50 (mg/kg/day)Approximate ED30 (mg/kg/day)Dose that Achieved a Maximum Response (mg/kg/day)
Loss of body weight gainThymus involutionSerum osteocalcinFemur growth plate width
RU248580.61.0103
budesonide0.550.7512.710
prednisolone1–35100>100