Table II.

Effects of anti-C5a on parameters of MOF

OrganParameterGroups
Sham + preimmune IgGCLP + preimmune IgGCLP + anti-C5a
BloodLactate (nmol/L)2.87 ± 0.407.42 ± 1.313.54 ± 0.30
LiverBilirubin (mg/dl)0.30 ± 0.010.53 ± 0.080.23 ± 0.03
ALT (U/L)46.6 ± 1.8255.0 ± 65.263.6 ± 2.4
AST (U/L)74.0 ± 2.0386.6 ± 71.6128.0 ± 8.5
LDH (U/L)288.3 ± 85.8926.0 ± 47.0628.0 ± 11.5
KidneyCreatinine (mg/dl)0.43 ± 0.030.70 ± 0.050.43 ± 0.06
BUN (mg/dl)11.6 ± 1.444.5 ± 12.217.6 ± 0.7
Urine protein (mg/dl)1.30 ± 0.043.27 ± 0.291.57 ± 0.19
Urine output (ml/36 h)26.2 ± 0.86.6 ± 1.019.0 ± 1.0
GFR (ml/min)1.89 ± 0.030.49 ± 0.071.90 ± 0.24