Table I.

Arterial blood gas analyses

ParameterEarly Phase (24 h)Late Phase (60 h)
ControlCLP + preimmune IgGCLP + anti-C5aControlCLP + preimmune IgGCLP + anti-C5a
pH7.47 ± 0.017.53 ± 0.01*7.49 ± 0.017.48 ± .0037.34 ± .008*7.49 ± .003
pCO2 (mmHg)38.6 ± 0.8934.2 ± 0.91*37.2 ± 0.6236.6 ± 1.2944.5 ± 3.3237.9 ± 2.34
HCO3 (mmol/L)26.4 ± 1.1426.9 ± 0.5028.1 ± 0.7626.6 ± 0.4720.8 ± 1.86*26.4 ± 1.14
pO2 (mmHg)106 ± 0.88106.4 ± 7.86112.5 ± 2.50105 ± 0.8869.8 ± 9.79*106 ± 4.17
  • a , Significant difference (p < 0.05) vs effects of anti-C5a treatment.