Costimulatory effects of TGF-β on alloactivated naive T cellsa
| Control (%) | TGF-β (%) | p | |
|---|---|---|---|
| CD25 | 34.5 ± 3.8 | 42.3 ± 3.6 | <0.01 |
| CTLA-4 | |||
| Intracellular | 23.2 ± 4.5 | 31.5 ± 4.1 | <0.01 |
| Surface | 5.2 ± 0.4 | 10.8 ± 0.9 | <0.01 |
a CD45RO-depleted CD4+ cells were stimulated with irradiated allogeneic non-T cells for 5 days with or without TGF-β and stained for the markers indicated as described in Materials and Methods. p values were determined using the paired t test. N = 13.