Table III.

3C8 cells mediate protection against L. monocytogenes infectiona

OrganLog10 CFUΔLog10 Protection
Control3C8
Spleen7.5 ± 0.36.5 ± 0.5*1.0
Liver7.1 ± 0.94.9 ± 0.7†2.2
  • a C57BL/6 mice received 107 3C8 cells i.v. in 200 μl PBS, or PBS alone (control), and were then infected with a lethal dose of L. monocytogenes (105 CFU i.v.). Bacterial load in the liver and spleen were determined 72 h after infection. Data are mean log10 CFU ± SD, n = 5 mice per group. *, p < 0.02 vs control. †, p < 0.01 vs control.