Table I.

fMIGWII immunization does not protect against L. monocytogenesa

ImmunizationLog10 CFU
LiverSpleen
IFA3.9 ± 0.35.6 ± 0.3
IFA+ fMIGWII3.5 ± 0.25.3 ± 0.6
L. monocytogenes <2.32.3 ± 0.3
  • a C57BL/6 mice were immunized s.c. with 100 μg fMIGWII in IFA on days 0 and 10, or infected with 103 CFU. L. monocytogenes i.v. on day 0. On day 20 mice were challenged with 5 × 103 CFU L. monocytogenes i.v. Bacterial load in the liver and spleen were determined 4 days later. Data are mean log10 CFU ± SD, n = 4 mice per group.