Table I.

Number of germinal centers in Cr2−/− micea

DayCr2+/+Cr2−/−
09 ± 27 ± 1
656 ± 420 ± 3
846 ± 320 ± 2
1082 ± 315 ± 1
1229 ± 218 ± 1
  • a Data are from three 9- to 12-wk-old mice per group. Numbers represent the average number of spleen germinal centers ± SEM from four different discontinuous spleen sections per animal so that the average amount of germinal centers in twelve different slides was determined for each experimental group. The area of the sections were 40 mm2 each. For all values, p < 0.001 as determined using the Student’s t test.