Table II.

Generation of CD4CD8 (DN) thymocytes and lymph node T cells

ζ Transgene2C 1B2+ DN
Thymusaζ+/+5.3 ± 1.0 (n = 7)
ζ-3 ITAM6.2 ± 1.2 (n = 7)
ζ-1 ITAM3.8 ± 0.9 (n = 7)
ζ-0 ITAM1.0 ± 0.6 (n = 9)
Lymph Nodebζ+/+12.7 ± 3.2 (n = 7)
ζ-3 ITAM12.7 ± 2.3 (n = 6)
ζ-1 ITAM5.9 ± 2.0 (n = 7)
ζ-0 ITAM1.0 ± 0.5 (n = 9)
  • a Absolute number (×106) of DN clonotype-positive thymocytes.

  • b Percent of DN clonotype-positive lymph node cells.