Table I.

Increase of Gr-1+ and Mac-1+ cell population in BM and spleen of MCA-26 tumor-bearing mice, as detected by flow cytometry

Marker% of Positive Cells
SC naiveaSC TBBM naiveBM TB
Gr-1+13.2 ± 1.248.3 ± 2.441.7 ± 6.380.9 ± 5.3
Mac-1+6.6 ± 0.845.8 ± 2.648.1 ± 11.790.1 ± 1.9
Gr-1+/Mac-1+2.8 ± 0.343.8 ± 2.534.5 ± 3.879.3 ± 1.3
  • a Fresh-derived spleen or BM cells after erythrocyte depletion were used for staining. The results shown are representative of three separate experiments. TB, tumor-bearing cells.