Table I.

Effect of LPS and MPL administration on the recovery of spleen DC subpopulations

Dendritic Cells per Spleen (×10−6)a
Total DCbCD4+8CD48CD48+
Control2.00.90.50.4
LPS1.30.30.70.2
MPL2.10.90.50.5
  • a DC were extracted 18 h after adjuvant administration. Each result is the mean of three experiments. Each experiment involved the pooled spleens of eight mice.

  • b Around 10% of the total DC were excluded in the gatings used to define the three DC subpopulations.