Table II.

Statistical analysis of the data of several independent experiments concerning the peptide-mediated inhibition of endotoxin-induced TNF-α releasea

Inhibition of TNF-α Release by ANA-1 Cells: Comparison BetweenInhibition of TNF-α Release by Mono Mac 6 Cells: Comparison BetweenInhibition of TNF-α Release In Vivo: Comparison Between
Peptide 1Peptide 2ResultαbPeptide 1Peptide 2ResultαPeptide 1Peptide 2Resultα
NEU-10PA-10H0c0.520NEU-10PA-10H00.591NEU-10PA-10H00.725
PMBPA-10H1d>0.001PMBPA-10H10.004PMBPA-10H1>0.001
LALF-22PA-10H10.001LALF-22PA-10H00.709LALF-22PA-10H10.008
H-14PA-10H00.310H-14PA-10H00.624H-14PA-10H00.276
B-14PA-10H00.274B-14PA-10H00.762B-14PA-10H00.604
LALF-14PA-10H00.426LALF-14PA-10H00.528LL-10PA-10H00.371
LL-10-H-14PA-10H1>0.001LL-10-H-14PA-10H10.007LALF-14PA-10H00.126
B-10-H-14PA-10H00.947B-10-H-14PA-10H00.805LL-10-H-14PA-10H1>0.001
LL-10+ H-14PA-10H00.612LL-10+ H-14PA-10H00.614B-10-H-14PA-10H00.734
LL-10-H-14PMBH00.432LL-10-H-14PMBH00.784LL-10 + H-14PA-10H00.915
LL-10-H-14LALF-22H00.096LL-10-H-14LALF-22H10.006LL-10-H-14PMBH00.905
LL-10-H-14LALF-22H00.225
  • a Univariate analysis of variance.

  • b Probability of error.

  • c H0, no significant difference between two peptides, α >0.05.

  • d H1, significant difference between two peptides, α <0.05.