Table II.

Ab responses during infection with T. spiralisa

iNOS−/+iNOS−/−
Day 0Day 13 p.i.Day 0Day 13 p.i.
Parasite-specific IgG2a (A630)0.193 ± 0.0060.207 ± 0.0100.255 ± 0.0130.350 ± 0.013b c
Parasite-specific IgG1 (A630)0.165 ± 0.0041.071 ± 0.029b0.203 ± 0.0090.740 ± 0.023b c
Total IgE (μg/ml)9.6 ± 2.5943.8 ± 23.3b11.0 ± 3.53630.7 ± 64.8b c
  • a Data are shown as mean ± SEM; iNOS−/+ (n = 6); iNOS−/− (n = 7). This table is representative of two experiments.

  • b , Significant difference between infected and uninfected animals (p < 0.05).

  • c , Significant difference between iNOS−/+ and iNOS−/− (p < 0.05).