Table I.

Sequence, HLA-A*0201 binding affinity, and CD8+ T cell responses to MDP-derived epitopes

RegionSequenceAffinity (nM)Ex Vivo ResponseIn Vitro Secondary Response
Tyr369–377YMDGTMSQV74++
gp100154–62KTWGQYWQV20+
gp100476–485VLYRYGSFSV24+
gp100457–466LLDGTATLRL19
gp100209–217ITDQVPFSV70
gp100280–288YLEPGPVTA303