Table I.

PKO/GKO mice exhibit increased susceptibility to virulent LM compared to WT mice but similar resistance to ActA-deficient LMa

LM StrainWT (H-2d), log 10 LD50PKO/GKO (H-2d), log 10 LD50
10403s (virulent)4.41.0
DP-L1942 (ActA)6.96.6
  • a WT BALB/c and PKO/GKO mice were infected with the indicated virulent (10403s) or attenuated (DP-L1942) LM strains and LD50s were estimated as described (13 ).