Table I.

Protection does not result from the dilution of diabetogenic T cellsa

Donor cellsIncidence of Diabetes (at wks)
Diabetic splenocytesNondiabetic45678
+3 /107 /1010 /10
+Spleen B cells5 /129 /1212 /12
+4 /65 /66 /6
+Bone marrow granulocytes2 /65 /65 /65 /66 /6
+0 /44 /4
+Splenocytes from NOD Cα−/−0 /43 /44 /4
  • a Splenocytes (4 × 105 CD62L T cell equivalents) from recently diabetic NOD mice were adoptively transferred into NOD.scid mice with or without 20 × 106 non-T cells from 5-wk-old NOD mice or NOD Cα−/− mice.