Table I.

Characteristics of IgA receptors

LigandsCell Types ExpressingDistinguishing Characteristics of Epithelial ReceptorRef.
New epithelial receptorSerum IgA1, IgA2, and aggregated IgAEpithelial cellsThis study
Mesangial cell receptorSerum IgA1, and aggregated IgAMesangial cellsNot known22
β-GalactosyltransferasePolymeric IgA, mIgA1/A2, S-IgALiver, myeloid, epithelial cellsCation-independent binding18
FcαR (CD89)IgA1, IgA2, S-IgAMyeloid cellsNo mRNA by RT-PCR; no staining with My435–15
pIgRPolymeric IgA, IgMSecretory epithelial cellsBinds mIgA; no inhibition by IgMReviewed in 4
ASGPRTerminal galactose and N-acetyl galactosamineLiver, myeloid epithelial cellsNo inhibition by asialoorosomucoid16, 17
S-IgARS-IgA/free SCEosinophils, basophilsBinds serum IgA, not S-IgA29, 30