Table II.

Leukocyte emigration ratio normalized by peripheral WBC counts

GenotypeEmigration Ratio (%)aDecrease of Emigration Ratio (%)b
LeukocytesNeutrophilsLeukocytesNeutrophils
WT78.3229.400
CD11a (−/−)12.110.3−84.6−95.5
WT67.8181.100
CD11b (−/−)226.1669.7+237.5+269.7
WT72.3189.000
CD18 (−/−)8.412.4−88.5−93.4
  • a Emigration ratio = (leukocytes in air pouch/peripheral leukocytes after injection of TNF-α) × 100%. Leukocyte numbers were determined at 4 h after injection of TNF-α.

  • b Percentage change of emigration ratio = [(leukocyte emigration ratio of knockout mice/leukocyte emigration ratio of WT mice) − 1] × 100%.