Table II.

Binding of phosphopeptides to class I MHC molecules

Peptide NameSequenceaProteinScoreC50 (μM)Ref.b
HLA-A*0201
OP42YAQPQTTTPLCRKL207–216+++136
OP42-PYAQPQTTTPL++++0.5
OP27GLLKLASPELc-JUN67–76+++137
OP27-PGLLKLASPEL+>20
HLA-B*0702
OP42YAQPQTTTPLCRKL207–216+>2036
OP42-PYAQPQTTTPL+>20
OP46KPFYVNVEFBCR174–182+++0.838
OP46-PKPFYVNVEF++3
P26SPIVPSFDMInfluenza virus NP473–481++339
P26-PSPIVPSFDM
HLA-B*3501
OP42YAQPQTTTPLCRKL207–216+++0.936
OP42-PYAQPQTTTPL+>20
OP46KPFYVNVEFBCR174–182+++1.638
OP46-PKPFYVNVEF++8
P26SPIVPSFDMInfluenza virus NP473–481+++0.539
P26-PSPIVPSFDM
HLA-B*2705
OP39SRHKKLMFKp53378–386++++0.540
OP39-PSRHKKLMFK
H-2Kb
K3FAPSNYPALSendai virus NP324–332+++0.27
K3-PFAPSNYPAL(analogue)+++0.2
H-2Db
K3FAPSNYPALSendai virus NP324–332+++0.017
K3-PFAPSNYPAL(analogue)+++0.01
H-2Kk
P9SDEKAASPIInfluenza virus NP467–475++>2039
P9-PSDEKAASPI+>20
P10IDEKLSEILRSV RNA pol138–146+++0.616
P10-PIDEKLSEIL
P49DDSHFVSIInfluenza virus M287–94+++141
P49-PPDDSHFVSI
P49-P1DDSHFVSI
P49-P2DDSHFVSI
  • a Phosphorylated residues are underlined, and phosphopeptides are designated with “−P.”

  • b All peptides contain a natural phosphorylation site.