Table IV.

Rescue of anergic T cellsa

MediumICA69Tep69GAD65OVA
IDDM
Medium1129
IL224365572510345342216
ICA6913821171
Tep69144014201295
GAD651479126812661184
OVA12891098130612401105
PI29809431818178603113
IA232447864771773893052
Tetanus58791220411640111375412
Sib
Medium1224
IL219982403221845842149
ICA6913821234
Tep69144011861261
GAD651379132214681244
OVA10881077120913101187
PI13301573141014611259
IA214421242136513481086
Tetanus64306653659189276317
  • a Rescue of anergic T cells by costimulation with the “non-anergic” diabetes-associated Ags, PI or IA2 or with tetanus toxoid. Mean thymidine incorporation (cpm) in cultures stimulated as indicated. Redundant entries are blank. SD were within ±10%. Thirteen additional patients and four sibs were tested with similar results.