Table III.

Relative contributions to IFN-γ-expressing cell populations by NK and T cells following LPS challengea

GroupRelative % IFN-γ+ Cells
NKCD4 TCD8 T
4 h LPS100bBLDbBLDb
6 h LPS100BLDBLD
Day 7 LCMV+ 4 h LPS3.9 ± 0.912.6 ± 1.283.6 ± 2.1
Day 7 LCMV+ 6 h LPS4.3 ± 1.514.7 ± 1.381.0 ± 0.5
  • a Relative percentages, as described in Materials and Methods, were calculated by combining total splenic cell yields, and determing relative numbers of NK, CD4, and CD8 cells expressing IFN-γ. Results are expressed as mean ± SEM, with 3 C57BL/6 mice per group, except where indicated.

  • b Value calculated from one mouse.