Relative contributions to IFN-γ-expressing cell populations by NK and T cells following LPS challengea
Group | Relative % IFN-γ+ Cells | ||
---|---|---|---|
NK | CD4 T | CD8 T | |
4 h LPS | 100b | BLDb | BLDb |
6 h LPS | 100 | BLD | BLD |
Day 7 LCMV+ 4 h LPS | 3.9 ± 0.9 | 12.6 ± 1.2 | 83.6 ± 2.1 |
Day 7 LCMV+ 6 h LPS | 4.3 ± 1.5 | 14.7 ± 1.3 | 81.0 ± 0.5 |
a Relative percentages, as described in Materials and Methods, were calculated by combining total splenic cell yields, and determing relative numbers of NK, CD4, and CD8 cells expressing IFN-γ. Results are expressed as mean ± SEM, with 3 C57BL/6 mice per group, except where indicated.
b Value calculated from one mouse.