Table III.

Immunological and virological characteristics and lymphoproliferative responses of patients with major/minor or single/none pattern of CD8 clonal dominance

Major + Minor (n = 12)Single + None (n = 10)p Values
Age (yr)6.8 ± 4.49.8 ± 3.2NS
V.L. (log10)a4.1 ± 1.14.8 ± 0.7NS
% CD428.3 ± 11.68.6 ± 4.8<0.001
% CD838.3 ± 10.147.5 ± 15.5NS
DR+CD38+b37.4 ± 13.154.6 ± 14.2<0.01
LPA
PHA400.2 ± 518.5258.4 ± 144.7NS
Candida 92.0 ± 59.512.3 ± 14.40.002
Tetanus76.3 ± 51.211.2 ± 12.70.002
MLC178.3 ± 298.932.9 ± 35.2<0.001
  • a V.L. = Plasma HIV RNA (log10)

  • b Expressed as % CD8 cells.