Table I.

Identification of potential HLA A2-binding peptides within gp85 and gp350a

RankingResiduePeptide SequenceScoreb
gp851177–185FLMGTYKRV1775.663\E
2317–325WLAKSFFEL1082.903\E
3672–680GLYEERAHV912.522\E
4685–693ILYFIAFAL674.026\E
52–10QLLCVFCLV488.951\E
6225–233SLVIVTTFV382.536\E
7681–689VLAIILYFI224.537\E
8684–692IILYFIAFA196.407\E
9542–550LMIIPLINV181.738\E
101–9MQLLCVFCL181.738\E
117–15FCLVLLWEV133.298\E
12658–666YLLLTTNGT126.883\E
13420–428TLFIGSHVV105.510\E
gp350\E1871–879VLTLLLLLV271.948\E
2152–160LIPETVPYI126.481
3863–871VLQWASLAV118.238\E
4875–883LLLLVMADC71.872\E
567–75QLTPHTKAV69.552\E
6861–869MLVLQWASL61.737\E
7873–881TLLLLLVMA42.278
  • a To identify the potential HLA A2-binding peptides within gp85 and gp350, a computer-based program was employed as described elsewhere (18). This program can be directly accessed through http.//bimas.dcrt.nih.gov/molbio/hla bind/index.html.

  • b Estimate half-time disassociation from HLA A2 allele.