Table II.

mIL-17R:Fc prolongs MHC mis-matched vascularized heart allograft survivala

Dosage, μg/day (timing)Graft Survival Time (days)Mean Survival Time (days)Median Survival Time (days)
None8, 9, 10, 10, 11, 12, 12, 1310.6 ± 1.710.5
200 (days 0–3)7, 9, 11, 1310.0 ± 2.610
200 (days 0–6)10, 12, 12, 13, 17, 21, 22, 3517.8 ± 8.215
500 (days 0–6)14, 14, 16, 19, 19, 22, 23, 36, 4823.4 ± 11.419b
  • a The strain combination was B10 (H2b) to C3H (H2k).

  • b p < 0.0001 when compared to the control group.