Table III.

Precursor frequency analysis of mutations in HK/156/97 and HK/483/97 using ELISPOT assay

DonorProtein SpecificityEpitopeVirus StrainPrecursor CTL FrequencyPeptide Sequence
1NP174–184A/PR/8/341/4,348R R S G A A G A A V K
A/HK/156/971/5,263*** ****** I*
1M117–31A/PR/8/341/50,000S G P L K A E I A Q R L E D V
A/HK/483/97<1/500,000****** Q****** **
  • ∗, Same amino acid as above.