Table I.

Renal pathology in γδ T cell-deficient IFN-γ transgenic micea

AnimalGlomerular Pathology
GL/HCFibrinCrescentsPMN
γδ Het
1
2
3−/+
4++
5−/+
6
7+
8
9
10
11+
γδ KO
12−/+
13−/+
14++++
15−/+
16++
17
18
19++
  • a γδ Het and γδ KO, IFN-γ transgenic animals heterozygous and homozygous for the TCR δ-chain deletion, respectively; GL/HC, glomerular hypercellularity (−/+, equivocal; +, mild; ++, moderate; +++, severe); PMN, infiltrate of polymorphonuclear leukocytes.