Table III.

Analysis of the inhibitory receptor repertoire in B6, D8, and B6DP mice

Mouse strainExpression Level of Ly49 Receptors on NK1.1+ CellsaNumber of Ly49+/NK1.1+ Cellsb
Ly49ALy49C/ILy49G2Ly49ALy49C/ILy49G2
B610010010021 ± 257 ± 1149 ± 5
D833 ± 594 ± 473 ± 818 ± 347 ± 1837 ± 8
B6DP67 ± 6c111 ± 1168 ± 325 ± 449 ± 1148 ± 5
  • a MFI (± SD) from three to five independent experiments. Ly49A, stained with A1 mAb; Ly49G2, 4D11 mAb; Ly49C/I, SW5E6 mAb. The fluorescence intensity on B6 was set to 100.

  • b Mean number of NK1.1+ cells ± SD expressing Ly49A, Ly49G2, or Ly49C/I.

  • c Significantly (p < 0.05) different from the expression on D8 NK1.1+ cells. Statistically significant differences were assessed using paired Student’s t test.