Table I.

Lysis of RBL-5, RBL-5Dd, and RBL-5Dp tumor cell targets by Ly49A+/NK1.1+ and Ly49A/NK1.1+ cells from B6 mice (% specific lysis)a

Target CellEffector Cells
Ly49A+Ly49ALy49A+ vs Ly49Ab
RBL-524.1 ± 10.925.5 ± 11.3p = 0.8
RBL-5Dd 7.2 ± 4.8 28.3 ± 8.8p < 0.0001
RBL-5Dp 10.3 ± 7.7 19.9 ± 8.6p < 0.0001
  • a Mean lysis values (± SD) from 10 independent experiments at E:T ratio 10:1. Values significantly (p < 0.05) different from RBL-5 tumor cell target are in bold. Statistically significant differences were assessed using paired Student’s t test.

  • b Comparison of the lysis by Ly49A+ and Ly49A NK cells of each target. Statistically significant differences were assessed using paired Student’s t test.