Table I.

Cell populations ×106 in the spleens of mice infected with M. avium 25291 SmTa

1 mo.2 mo.4 mo.
iNOS+/+iNOS−/−iNOS+/+iNOS−/−iNOS+/+iNOS−/−
Total77.0 ± 8.3122.5 ± 22.4135.6 ± 9.0259.6 ± 46.7*61.0 ± 7.844.2 ± 10.2
CD4+17.5 ± 3.126.6 ± 7.631.2 ± 4.152.0 ± 20.78.1 ± 1.44.7 ± 1.8*
(22.7%)(21.7%)(23.0%)(20.0%)(13.3%)(10.6%)
CD8+8.7 ± 2.011.0 ± 5.914.2 ± 2.220.3 ± 7.32.9 ± 0.51.2 ± 0.4**
(11.3%)(9.0%)(10.5%)(7.8%)(4.8%)(2.7%)
  • a Statistical analysis was performed using the Student’s t test. Statistically significant differences are labeled * for p < 0.05 and ** for p < 0.001.