Table III.

Mononuclear cells localized in the outer ear during auricular chondritis in HLA-DQ6αβ/8αβ tg micea

Surface Molecule ExpressionNormal Ears (nondiseased)Acute Chondritic Ears (1 wk postonset)Chronic Chondritic Ears (8 wk postonset)
CD3++
CD4+
CD8+
B220+/−
CD11b/Mac 1++++++++
  • a Sections of chondritic and normal DQ6αβ/8αβ tg ears were incubated with mAbs specific for the indicated cell surface molecules and scored for the presence of positive cells as follows: −, no positive cells detected; +/−, <5% positive; +, 5–10% positive; ++, 11–20% positive; +++, 21–50% positive; and ++++, >50% positive cells.