Table II.

Summary of polychondritis in DQ6αβ/8αβ mice

Mouse StrainAuricular ChondritisPolyarthritis
% Incidence (chondritic/total)Day of onset ± SEa% Incidence (arthritic/total)Day of onset ± SEaMean peak severity ± SEa
DQ6αβ/8αβ tg25.3 (21/83)51 ± 1271.4 (59/83)36 ± 36.3 ± 0.4
DQ6αβ/8αβ tg neg0.0 (0/19)0.0 (0/19)
DQ6αβ tg0.0 (0/12)8.3 (1/12)523
DQ8αβ tg0.0 (0/14)78.6 (11/14)39 ± 45.9 ± 0.9
B10.T (6R)0.0 (0/38)57.9 (22/38)44 ± 24.0 ± 0.3
  • a Day of onset of auricular chondritis and polyarthritis as well as the severity of arthritis was calculated only from affected mice displaying the pertinent symptom.