Table III.

IFN-γ induces TNF-α in MRL-Faslpr mesangial cellsa

(pg/ml)MRL-Faslpr
IFN-γR−/−IFN-γR+/−
Media140
IFN-γ0265*
  • a TNF-α was detected by ELISA. Mesangial cells from IFN-γR-deficient and intact MRL-Faslpr mice stimulated with rIFN-γ at 50 U/ml or media alone. *p < 0.001 vs media alone, Mann-Whitney test.