Table VII.

Identified T cell epitopes in melanosomal Ags in human

ProteinRestricting HLAEpitope SequenceRef.
TyrosinaseHLA-A*0201MLLAVCYLL21
HLA-A*0201YMDGTMSQV21, 34
HLA-A1DAEKCDKTDEY18
HLA-A1SSDYVIPIGTYThis study
HLA-A*2402AFLPWHRLF10
HLA-B44SEIWRDIDF24
HLA-DR4QNILLSNAPLGPQFP26
HLA-DR4SYLQDSDPDSFQD26
gp100HLA-A*0201KTWGQYWQV8, 35
HLA-A*0201AMLGTHTMEV20
HLA-A*0201MLGTHTMEV20
HLA-A*0201ITDQVPFSV8
HLA-A*0201YLEPGPVTA8, 36
HLA-A*0201LLDGTATLRL8
HLA-A*0201VLYRYGSFSV8
HLA-A*0201SLADTNSLAV20
HLA-A*0201RLMKQDFSVThis study
HLA-A*0201RLPRIFCSCThis study
HLA-A3ALLAVGATK22
HLA-A3LIYRRRLMKThis study
HLA-A*2402VYFFLPDHL23
MART-1/Melan-AHLA-A*0201AAGIGILTV6
HLA-A*0201ILTVILGVL19
HLA-B*4501AEEAAGIGILT25
TRP1HLA-A31MSLQRQFLR11
TRP2HLA-A*0201SVYDFFVWL32
HLA-A31LLPGGRPYR13
HLA-A33LLPGGRPYR