Table I.

TNF-α/IFN-γ treatment inhibits invasion of glioma cells

Cell Treatment([3H]TdR) of Invaded Cells% Inhibition
U251-MG
Controla54,389 ± 2,206b
TNF-α/IFN-γc10,614 ± 2,334d80e
CRT
Controla8,675 ± 512b
TNF-α/IFN-γc1,041 ± 85d88e
  • a Medium alone for 72 h.

  • b Mean ± SD of triplicate samples; representative of three independent experiments.

  • c TNF-α (50 ng/ml) plus IFN-γ (100 U/ml) for 72 h.

  • d Significantly different from Control (p < 0.01).

  • e Compared to Control values.