Table II.

TIL recognition of AdVMART1-transduced cellsa

StimulatorTNF-β Release (pg/ml)IFN-γ Release (pg/ml)
T2+ MART-180NTb
T2+ MAGE-332NT
T2 only32NT
AdVMART1/DC55500
AdVRR5/DC3025
Background3655
  • a MART-1 specificity of melanoma patient TIL was confirmed by TNF-β release using T2 cells pulsed with peptides as stimulator cells. TIL recognition of AdVMART1-transduced DC was assessed by both TNF-β and IFN-γ release. All ELISA samples were performed in duplicate.

  • b NT, not tested.