Table III.

Absolute numbers of total cells, mononuclear cells, neutrophils, and eosinophils in BALF of OVA-sensitized mice treated either with control Ab or with Abs to IL-16 during the OVA or saline challenge perioda

TreatmentGroupTotal Cells (×10−5)Mononuclear Cells (×10−5)Neutrophils (×10−3)Eosinophils (×10−3)
Control AbOA5.7 ± 1.05.0 ± 0.63.5 ± 1.724.0 ± 13.0*
SAL7.1 ± 1.27.1 ± 1.21.8 ± 1.40.0 ± 0.0
Anti-IL-16OA4.6 ± 0.74.4 ± 0.72.7 ± 1.215.9 ± 8.4*
SAL4.4 ± 0.54.3 ± 0.64.7 ± 2.10.0 ± 0.0
  • a Values are expressed as mean ± SEM. OA, OVA-challenged mice, SAL, saline-challenged mice. *, Significantly different from saline-challenged mice. Among OVA- and saline-challenged groups, no significant difference was observed in the number of total cells, the number of mononuclear cells, or the number of neutrophils. Compared with control antibody, treatment with Abs to IL-16 had no significant effect on the absolute number of any cell type evaluated.